| CASE REPORT |
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| Year : 2022 | Volume
: 31
| Issue : 1 | Page : 165-167 |
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Benzodiazepine withdrawal catatonia: Two cases from a tertiary care center in Eastern India
Uttam Majumder, Avik K Layek
Department of Psychiatry, North Bengal Medical College, Sushrutanagar, Darjeeling, West Bengal, India
Correspondence Address:
Dr. Avik K Layek
Department of Psychiatry, North Bengal Medical College, Sushrutanagar, Darjeeling - 734 012, West Bengal
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ipj.ipj_265_21
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Catatonia is a diagnostic entity of a neuropsychiatric cluster of symptoms that can occur in a number of different psychiatric, neurologic, and metabolic disorders. Benzodiazepines remain the mainstay of the treatment of catatonia through their possible effect on the gamma-aminobutyric acid (GABA) receptor modulation in the central nervous system (CNS). Rarely, patients have been seen to manifest catatonic symptoms when they face sudden withdrawal from long-term benzodiazepine treatment. Here, we have presented two such cases of different clinical profiles where following benzodiazepine withdrawal, sudden catatonic symptoms emerged that responded quickly on re-administration of benzodiazepines.
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